Nurr1 performs the anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation
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چکیده
منابع مشابه
Anti-inflammatory effect of Allium akaka extract on the inflammation induced by carrageenan in rats
Background and objectives: Allium akaka, locally known “Valak” a member of the Amaryllidaceae family, is widely used in Iranian folk medicine for its wound healing, antibacterial, anthelmintic, and diuretic properties. The aim of the present work was to evaluate the anti-inflammatory effect of Allium akaka hydro-alcoholic extract on carrageenan-induce...
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Advances in neonatal care have allowed premature infants to survive at earlier gestational ages, but they are often afflicted with neurological delays or deficits. Maternal inflammation has been identified as a major risk factor for premature birth and once born, infants often require supplemental oxygen for survival. Nurr1 (NR4A2) is an orphan nuclear receptor with no known binding site and is...
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Platelet-activating factor (PAF) is one of the most potent lipid mediators involved in inflammatory events. The acetyl group at the sn-2 position of its glycerol backbone is essential for its biological activity. Deacetylation induces the formation of the inactive metabolite lyso-PAF. This deacetylation reaction is catalyzed by PAF-acetylhydrolase (PAF-AH), a calcium independent phospholipase A...
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ژورنال
عنوان ژورنال: IBRO Reports
سال: 2019
ISSN: 2451-8301
DOI: 10.1016/j.ibror.2019.07.923